This is a program of the U.S. Department of Health and Human Services, Office of Public Health Emergency Medical Countermeasures, and the National Institutes of Health. The program is coordinated by NIAID, with the involvement of the National Cancer Institute. The Strategic Plan and Research Agenda is intended to unify and strengthen the radiation research community, promote increased collaboration, and facilitate transition from research to product development. NIH will work closely with HHS to prioritize the research and development activities in this ambitious agenda with the resources available and as one component of the larger national biodefense research agenda.
The purpose of this Funding Opportunity Announcement (FOA) is to encourage and support planning efforts for establishing a center for Particle Beam Radiation Therapy (PBRT) Research. The Center must be planned to operate as a research center adjunct to an independently created and funded, sustainable clinical facility for PBRT. The P20 research grants have been awarded. For more information about these awards, see the NIH RePORTER Search Results.
A Prospective Randomized Phase 3 Trial of Carbon Ion versus Conventional Radiation Therapy for Locally, Advanced, Unresectable Pancreatic Cancer
The overall objective of this Broad Agency Announcement (BAA) is to conduct a definitive randomized phase 3 clinical trial of carbon ion radiotherapy vs. 3D conformal radiation therapy for unresectable pancreatic cancer. The clinically relevant outcomes of this trial shall also be indirectly compared to those of parallel trial, RTOG1201, carried out by NRG Oncology, a member organization of the NCI Clinical Trials Network (NCTN).
DOE and NCI cosponsored a workshop on ion beam therapy that helped define the needs and challenges of particle beam therapies and particle accelerators.
The Planning Guidance focuses on topics relevant to emergency planning within the first few days of nuclear detonation including: 1) shelter and evacuation, 2) medical care, and 3) population monitoring and decontamination. This guidance was developed by a Federal interagency committee led by the Executive Office of the President (National Security Staff and Office of Science and Technology Policy) with representatives from several federal U.S. Departments.
Quantitative Imaging for Response Assessment
This network is one of several being conducted within the Cancer Imaging Program. It is designed to promote research and development of quantitative imaging methods for the measurement of tumor response to therapies in clinical trial settings, with the overall goal of facilitating clinical decision making. Projects include the appropriate development and adaptation/implementation of quantitative imaging methods, imaging protocols, and software solutions/tools (using existing commercial imaging platforms and instrumentation) and application of these methods in current and planned clinical therapy trials.
The Cancer Imaging Archive (TCIA) is provided by the Cancer Imaging Program (CIP) as a service to the research community. TCIA provides a freely accessible, open archive of cancer-specific medical images and metadata accessible for public download. A huge amount of clinical and research images are collected each year with many high value data sets already available.