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Last Updated: 06/19/18

Selected RRP Staff Publications

Selected RRP publications 2010 to present:

The Use of Quantitative Imaging in Radiation Oncology: A Quantitative Imaging Network (QIN) Perspective
Robert H. Press, Hui-Kuo G. Shu, Hyunsuk Shim, James M. Mountz, Brenda F. Kurland, Richard L. Wahl, Ella F. Jones, Nola M. Hylton, Elizabeth R. Gerstner, Robert J. Nordstrom, Lori Henderson, Karen A. Kurdziel, Bhadrasain Vikram, Michael A. Jacobs, Matthias Holdhoff, Edward Taylor, David A. Jaffray, Lawrence H. Schwartz, David A. Mankoff, Paul E. Kinahan, Hannah M. Linden, Philippe Lambin, Thomas J. Dilling, Daniel L. Rubin, Lubomir Hadjiiski, John M. Buatti. International Journal of Radiation Oncology, Biology, Physics. (in press 2018)

Microarray analysis of miRNA expression profiles following whole body irradiation in a mouse model.
Aryankalayil MJ, Chopra S, Makinde A, Eke I, Levin J, Shankavaram U, MacMillan L, Vanpouille-Box C, Demaria S, Coleman CN. Biomarkers. 2018 May 25:1-26. PMID: 29799276

Radiation Oncology in the 21st Century: Prospective Randomized Trials That Changed Practice… or Didn't!
Zakeri K, Coleman CN, Vikram B. Front Oncol. 2018 Apr 30;8:130. Review. PMID: 29761073

The Future of Radiobiology.
Kirsch DG, Diehn M, Kesarwala AH, Maity A, Morgan MA, Schwarz JK, Bristow R, Demaria S, Eke I, Griffin RJ, Haas-Kogan D, Higgins GS, Kimmelman AC, Kimple RJ, Lombaert IM, Ma L, Marples B, Pajonk F, Park CC, Schaue D, Tran PT, Willers H, Wouters BG, Bernhard EJ. J Natl Cancer Inst. 2018 Apr 1;110(4):329-340. PMID: 29126306

Do protons and X-rays induce cell-killing in human peripheral blood lymphocytes by different mechanisms?
Miszczyk J, Rawojć K, Panek A, Borkowska A, Prasanna PGS, Ahmed MM, Swakoń J, Gałaś A. Clin Transl Radiat Oncol. 2018 Jan 31;9:23-29. doi: 10.1016/j.ctro.2018.01.004. eCollection 2018 Feb. PMID:29594247

Accurate, Precision Radiation Medicine: A Meta-Strategy for Impacting Cancer Care, Global Health, and Nuclear Policy and Mitigating Radiation Injury From Necessary Medical Use, Space Exploration, and Potential Terrorism.
Coleman CN, Prasanna PGS, Bernhard EJ, Buchsbaum JC, Ahmed MM, Capala J, Obcemea C, Deye JA, Pistenmma DA, Vikram B, Bernier J, Dosanjh M., Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):250-253. PMID: 29726348

The pervasive crisis of diminishing radiation therapy access for vulnerable populations in the United States, part 2: American Indian patients.
McClelland S 3rd, Leberknight J, Guadagnolo BA, Coleman CN, Petereit DG. Adv Radiat Oncol. 2017 Aug 26;3(1):3-7. PMID: 29556572

Current and Future Initiatives for Radiation Oncology at the National Cancer Institute in the Era of Precision Medicine.
Kunos CA, Coleman CN. Int J Radiat Oncol Biol Phys. 2018 Jan 8. pii: S0360-3016(17)30644-2. PMID: 29325810

Radiation-Induced Long Noncoding RNAs in a Mouse Model after Whole-Body Irradiation.
Aryankalayil MJ, Chopra S, Levin J, Eke I, Makinde A, Das S, Shankavaram U, Vanpouille-Box C, Demaria S, Coleman CN. Radiat Res. 2018 Mar;189(3):251-263. PMID: 29309266

Exploiting Radiation-Induced Signaling to Increase the Susceptibility of Resistant Cancer Cells to Targeted Drugs: AKT and mTOR Inhibitors as an Example.
Eke I, Makinde AY, Aryankalayil MJ, Sandfort V, Palayoor ST, Rath BH, Liotta L, Pierobon M, Petricoin EF, Brown MF, Stommel JM, Ahmed MM, Coleman CN. Mol Cancer Ther. 2018 Feb;17(2):355-367. PMID: 28802252

Radiation-Induced Large Vessel Cerebral Vasculopathy in Pediatric Patients With Brain Tumors Treated With Proton Radiation Therapy.
Kralik SF, Watson GA, Shih CS, Ho CY, Finke W, Buchsbaum J. Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):817-824. PMID: 28867358

Radiation-agent combinations for glioblastoma: challenges in drug development and future considerations.
Kunos CA, Galanis E, Buchsbaum J, Shi Q, Strauss LC, Coleman CN, Ahmed MM. J Neurooncol. 2017 Sep;134(3):551-557. Review. PMID: 28560665

Implementing Cancer Care for the Undeserved Globally: From the "5 R's" of Radiobiology to the "7 P's" of Global Cancer Care.
Williams TR, Coleman CN. Semin Radiat Oncol. 2017 Apr;27(2):95-97. PMID: 28325247

Cancer Care Access and Outcomes for American Indian Populations in the United States: Challenges and Models for Progress.
Guadagnolo BA, Petereit DG, Coleman CN. Semin Radiat Oncol. 2017 Apr;27(2):143-149. Review. PMID: 28325240

Global Health in Radiation Oncology: The Emergence of a New Career Pathway.
Rodin D, Yap ML, Grover S, Longo JM, Balogun O, Turner S, Eriksen JG, Coleman CN, Giuliani M. Semin Radiat Oncol. 2017 Apr;27(2):118-123. Review. PMID: 28325237

Mobilising Expertise and Resources to Close the Radiotherapy Gap in Cancer Care.
Rodin D, Longo J, Sherertz T, Shah MM, Balagun O, Wendling N, Van Dyk J, Coleman CN, Xu MJ, Grover S. Clin Oncol (R Coll Radiol). 2017 Feb;29(2):135-140. PMID: 27955997

Radiation-Therapeutic Agent Clinical Trials: Leveraging Advantages of a National Cancer Institute Programmatic Collaboration.
Takebe N, Ahmed MM, Vikram B, Bernhard EJ, Zwiebel J, Norman Coleman C, Kunos CA. Semin Radiat Oncol. 2016 Oct;26(4):271-80. Review. PMID: 27619249

Radiotherapy: Changing the Game in Immunotherapy.
Demaria S, Coleman CN, Formenti SC. Trends Cancer. 2016 Jun;2(6):286-294. Review. PMID: 27774519

Radiation-Induced Fibrosis: Mechanisms and Opportunities to Mitigate. Report of an NCI Workshop, September 19, 2016.
Citrin DE, Prasanna PGS, Walker AJ, Freeman ML, Eke I, Barcellos-Hoff MH, Arankalayil MJ, Cohen EP, Wilkins RC, Ahmed MM, Anscher MS, Movsas B, Buchsbaum JC, Mendonca MS, Wynn TA, Coleman CN. Radiat Res. 2017 Jul;188(1):1-20. doi: 10.1667/RR14784.1. Epub 2017 May 10. PMID: 28489488

Comprehensive molecular tumor profiling in radiation oncology: How it could be used for precision medicine.
Eke I, Makinde AY, Aryankalayil MJ, Ahmed MM, Coleman CN. Cancer Lett. 2016 Nov 1;382(1):118-126. Review. PMID: 26828133

Masters of Our Destiny: From Jazz Quartet to Symphony Orchestra.
Coleman CN. Int J Radiat Oncol Biol Phys. 2016 Nov 1;96(3):511-3. PMID: 27681746

Exploiting Gene Expression Kinetics in Conventional Radiotherapy, Hyperfractionation, and Hypofractionation for Targeted Therapy.
Makinde AY, Eke I, Aryankalayil MJ, Ahmed MM, Coleman CN. Semin Radiat Oncol. 2016 Oct;26(4):254-60. Review. PMID: 27619247

Current Insights in Radiation Combination Therapies: Influence of Omics and Novel Targeted Agents in Defining New Concepts in Radiation Biology and Clinical Radiation Oncology.
Ahmed MM, Narendra A, Prasanna P, Coleman CN, Krishnan S. Semin Radiat Oncol. 2016 Oct;26(4):251-3. PMID: 27619246

Improving the Predictive Value of Preclinical Studies in Support of Radiotherapy Clinical Trials.
Coleman CN, Higgins GS, Brown JM, Baumann M, Kirsch DG, Willers H, Prasanna PG, Dewhirst MW, Bernhard EJ, Ahmed MM. Clin Cancer Res. 2016 Jul 1;22(13):3138-47. Review. PMID: 27154913

Preclinical Data on Efficacy of 10 Drug-Radiation Combinations: Evaluations, Concerns, and Recommendations.
Stone HB, Bernhard EJ, Coleman CN, Deye J, Capala J, Mitchell JB, Brown JM. Transl Oncol. 2016 Feb;9(1):46-56. Review. PMID: 26947881

Imaging and Data Acquisition in Clinical Trials for Radiation Therapy.
FitzGerald TJ, Bishop-Jodoin M, Followill DS, Galvin J, Knopp MV, Michalski JM, Rosen MA, Bradley JD, Shankar LK, Laurie F, Cicchetti MG, Moni J, Coleman CN, Deye JA, Capala J, Vikram B. Int J Radiat Oncol Biol Phys. 2016 Feb 1;94(2):404-11. Review. PMID: 26853346

A Roadmap for a New Academic Pathway for Global Radiation Oncology.
Olson AC, Coleman CN, Hahn SM, DeWeese TL, Shulman LN, Chabner BA, Chao N, Martei YM, Mundt AJ, Grover S. Int J Radiat Oncol Biol Phys. 2015 Nov 1;93(3):493-6. PMID: 26460990

UNITED STATES DEPARTMENT OF HEALTH AND HUMAN SERVICES BIODOSIMETRY AND RADIOLOGICAL/NUCLEAR MEDICAL COUNTERMEASURE PROGRAMS.
Homer MJ, Raulli R, DiCarlo-Cohen AL, Esker J, Hrdina C, Maidment BW, Moyer B, Rios C, Macchiarini F, Prasanna PG, Wathen L.Radiat Prot Dosimetry. 2016 Sep;171(1):85-98. doi: 10.1093/rpd/ncw226. Epub 2016 Sep 2. PMID:27590469

Radioprotectors and Radiomitigators for Improving Radiation Therapy: The Small Business Innovation Research (SBIR) Gateway for Accelerating Clinical Translation.
Prasanna PG, Narayanan D, Hallett K, Bernhard EJ, Ahmed MM, Evans G, Vikram B, Weingarten M, Coleman CN. Radiat Res. 2015 Sep;184(3):235-48. PMID: 26284423

Public health and medical preparedness for a nuclear detonation: the nuclear incident medical enterprise.
Coleman CN, Sullivan JM, Bader JL, Murrain-Hill P, Koerner JF, Garrett AL, Weinstock DM, Case C Jr, Hrdina C, Adams SA, Whitcomb RC, Graeden E, Shankman R, Lant T, Maidment BW, Hatchett RC. Health Phys. 2015 Feb;108(2):149-60. PMID: 25551496

High-throughput sample processing and sample management; the functional evolution of classical cytogenetic assay towards automation.
Ramakumar A, Subramanian U, Prasanna PG. Mutat Res Genet Toxicol Environ Mutagen. 2015 Nov;793:132-41. doi: 10.1016/j.mrgentox.2015.07.011. Epub 2015 Jul 28. PMID: 26520383

Response of human lymphocytes to proton radiation of 60 MeV compared to 250 kV X-rays by the cytokinesis-block micronucleus assay.
Miszczyk J, Rawojć K, Panek A, Swakoń J, Prasanna PG, Rydygier M. Radiother Oncol. 2015 Apr;115(1):128-34. doi: 10.1016/j.radonc.2015.03.003. Epub 2015 Mar 24. PMID: 25818831

National Cancer Institute's Cancer Disparities Research Partnership Program: Experience and Lessons Learned.
Wong RS, Vikram B, Govern FS, Petereit DG, Maguire PD, Clarkson MR, Heron DE, Coleman CN. Front Oncol. 2014 Nov 3;4:303. PMID: 25405101

The international cancer expert corps: a unique approach for sustainable cancer care in low and lower-middle income countries.
Coleman CN, Formenti SC, Williams TR, Petereit DG, Soo KC, Wong J, Chao N, Shulman LN, Grover S, Magrath I, Hahn S, Liu FF, DeWeese T, Khleif SN, Steinberg M, Roth L, Pistenmaa DA, Love RR, Mohiuddin M, Vikram B. Front Oncol. 2014 Nov 19;4:333. Review. PMID: 25478326

Combining targeted agents with modern radiotherapy in soft tissue sarcomas.
Wong P, Houghton P, Kirsch DG, Finkelstein SE, Monjazeb AM, Xu-Welliver M, Dicker AP, Ahmed M, Vikram B, Teicher BA, Coleman CN, Machtay M, Curran WJ, Wang D. J Natl Cancer Inst. 2014 Oct 18;106(11). pii: dju329. Review. PMID: 25326640

Enhancing the efficacy of radiation therapy: premises, promises, and practicality.
Coleman CN, Lawrence TS, Kirsch DG. J Clin Oncol. 2014 Sep 10;32(26):2832-5. PMID: 25113766

Bringing cancer care to the underserved globally: a challenging problem for which radiation oncology can pioneer novel solutions.
Coleman CN; many others. Int J Radiat Oncol Biol Phys. 2014 Jul 1;89(3):443-5. PMID: 24929152

Differential expression of stress and immune response pathway transcripts and miRNAs in normal human endothelial cells subjected to fractionated or single-dose radiation.
Palayoor ST, John-Aryankalayil M, Makinde AY, Falduto MT, Magnuson SR, Coleman CN. Mol Cancer Res. 2014 Jul;12(7):1002-15. PMID: 24784841

Radiation-induced brain damage, impact of Robbins’ work and the need for predictive biomarkers.
Prasanna PG, Ahmed MM, Stone HB, Vikram B, Mehta MP, Coleman CN. Int J Radiat Biol. 2014 May 21:1-50. PMID: 24844376.

Mitigating the risk of radiation-induced cancers: limitations and paradigms in drug development.
Yoo SS, Jorgensen TJ, Kennedy AR, Boice Jr JD, Shapiro A, Hu TC, Moyer BR, Grace MB, Kelloff GJ, Fenech M, Prasanna PG, Coleman CN. J Radiol Prot. 2014 Apr 14;34(2):R25-R52. PMID:24727460

Brachytherapy boost in loco-regionally advanced nasopharyngeal carcinoma: a prospective randomized trial of the International Atomic Energy Agency.
Rosenblatt E, Abdel-Wahab M, El-Gantiry M, Elattar I, Bourque JM, Afiane MH, Benjaafar N, Abubaker S, Chansilpa Y, Vikram B, Levendag P. Radiat Oncol. 2014 Mar 1; 9(1):67. PMID: 24581393

Premature chromosome condensation in human resting peripheral blood lymphocytes without mitogen stimulation for chromosome aberration analysis using specific whole chromosome DNA hybridization probes.
Pathak R, Prasanna PG. Methods Mol Biol. 2014; 1105:171-81. PMID:24623228

Assessment of biodosimetry methods for a mass-casualty radiological incident: medical response and management considerations.
Sullivan JM, Prasanna PG, Grace MB, Wathen LK, Wallace RL, Koerner JF, Coleman CN. Health Phys. 2013 Dec;105(6):540-54. PMID:24162058

mRNA Expression Profiles for Prostate Cancer following Fractionated Irradiation Are Influenced by p53 Status.
Simone CB 2nd, John-Aryankalayil M, Palayoor ST, Makinde AY, Cerna D, Falduto MT, Magnuson SR, Coleman CN. Transl Oncol. 2013 Oct 1;6(5):573-85. PMID:24151538

Nanotechnology in Radiation Research.
Rao V.L. Papineni, Pataje G.S. Prasanna, Mansoor M. Ahmed (2013). Society for Translational Cancer Research (Vol. 2). (K. Ji, Ed.) Sheung Wan, Hong Kong: Pioneer Bioscience Publishing Company.

G-CSF rescues tumor growth and neo-angiogenesis during liver metastasis under host angiopoietin-2 deficiency.
Im JH, Tapmeier T, Balathasan L, Gal A, Yameen S, Hill S, Smart S, Noterdaeme O, Kelly M, Brady M, Fu W, Kruse K, Bernhard EJ, Augustin HG, Muschel RJ. Int J Cancer. 2013 Jan 15;132(2):315-26. Epub 2012 Jul 3. PMID:22699974

NCI support for particle therapy: past, present, future.
Deye JA. Health Phys. 2012 Nov;103(5):662-6. PMID: 23032896

Redesigning radiotherapy quality assurance: opportunities to develop an efficient, evidence-based system to support clinical trials--report of the National Cancer Institute Work Group on Radiotherapy Quality Assurance.
Bekelman JE, Deye JA, Vikram B, Bentzen SM, Bruner D, Curran WJ Jr, Dignam J, Efstathiou JA, FitzGerald TJ, Hurkmans C, Ibbott GS, Lee JJ, Merchant TE, Michalski J, Palta JR, Simon R, Ten Haken RK, Timmerman R, Tunis S, Coleman CN, Purdy J. Int J Radiat Oncol Biol Phys. 2012 Jul 1;83(3):782-90. Epub 2012 Mar 15. PMID: 22425219

PET of HER2-positive pulmonary metastases with 18F-ZHER2:342 affibody in a murine model of breast cancer: comparison with 18F-FDG.
Kramer-Marek G, Bernardo M, Kiesewetter DO, Bagci U, Kuban M, Aras O, Zielinski R, Seidel J, Choyke P, Capala J. J Nucl Med. 2012 Jun;53(6):939-46. Epub 2012 May 11. Erratum in: J Nucl Med. 2012 Jul;53(7):1169. PMID:22582046

Normal tissue protection for improving radiotherapy: Where are the Gaps?
Prasanna PG, Stone HB, Wong RS, Capala J, Bernhard EJ, Vikram B, Coleman CN. Transl Cancer Res. 2012 Jun;1(1):35-48.PMID: 22866245

Potential of PET to predict the response to trastuzumab treatment in an ErbB2-positive human xenograft tumor model.
Kramer-Marek G, Gijsen M, Kiesewetter DO, Bennett R, Roxanis I, Zielinski R, Kong A, Capala J. J Nucl Med. 2012 Apr;53(4):629-37. Epub 2012 Mar 12.PMID: 22410461

68Ga-DOTA-affibody molecule for in vivo assessment of HER2/neu expression with PET.
Kramer-Marek G, Shenoy N, Seidel J, Griffiths GL, Choyke P, Capala J. Eur J Nucl Med Mol Imaging. 2011 Nov;38(11):1967-76. Epub 2011 Apr 20. PMID: 21748382

Biological Dosimetry by the Triage Dicentric Chromosome Assay - Further validation of International Networking.
Wilkins RC, Romm H, Oestreicher U, Marro L, Yoshida MA, Suto Y, Prasanna PG. Radiat Meas. 2011 Sep 1;46(9):923-928. PMID:21949482

New Translational Possibilities for Microenvironmental Modulation of Radiosensitivity.
Glazer PM, Le QT, Bristow R, Helleday T, Pelroy R, Bernhard EJ. Radiat Res. 2011 Jul 8. [Epub ahead of print] PMID: 21740252

Addressing Cancer Disparities Among American Indians through Innovative Technologies and Patient Navigation: The Walking Forward Experience.
Petereit DG, Guadagnolo BA, Wong R, Coleman CN. Front Oncol. 2011 Jun 22;1:11. eCollection 2011. PMID: 22649752

Disaster preparation: lessons from Japan.
Coleman CN, Simon SL, Noska MA, Telfer JL, Bowman T. Science. 2011 Jun 17;332(6036):1379. PMID:21680826

Unaltered ethical standards for individual physicians in the face of drastically reduced resources resulting from an improvised nuclear device event.
Caro JJ, Coleman CN, Knebel A, DeRenzo EG. J Clin Ethics. 2011 Spring;22(1):33-41. PMID: 21595353

Preparing and planning for a catastrophic incident of a nuclear detonation. Foreword.
Coleman CN, Knebel AR, Lurie N. Disaster Med Public Health Prep. 2011 Mar;5 Suppl 1:S11-2. PMID: 21402802

Scarce resources for nuclear detonation: project overview and challenges.
Coleman CN, Knebel AR, Hick JL, Weinstock DM, Casagrande R, Caro JJ, DeRenzo EG, Dodgen D, Norwood AE, Sherman SE, Cliffer KD, McNally R, Bader JL, Murrain-Hill P. Disaster Med Public Health Prep. 2011 Mar;5 Suppl 1:S13-9. PMID: 21402805

Low-dose fractionated radiation potentiates the effects of cisplatin independent of the hyper-radiation sensitivity in human lung cancer cells.
Gupta S, Koru-Sengul T, Arnold SM, Devi GR, Mohiuddin M, Ahmed MM. Mol Cancer Ther. 2011 Feb;10(2):292-302. Epub 2011 Jan 7. PMID: 21216938

Biological Dosimetry by the Triage Dicentric Chromosome Assay: Potential Implications for Treatment of Acute Radiation Syndrome in Radiological Mass Casualties.
Romm H, Wilkins RC, Coleman CN, Lillis-Hearne PK, Pellmar TC, Livingston GK, Awa AA, Jenkins MS, Yoshida MA, Oestreicher U, Prasanna PG. Radiat Res. 2011 Jan 4. PMID: 21204674

Establishment of a Radiogenomics Consortium
West C, Rosenstein BS, Alsner J, Azria D, Barnett G, Begg A, Bentzen S, Burnet N, Chang-Claude J, Chuang E, Coles C, De Ruyck K, De Ruysscher D, Dunning A, Elliott R, Fachal L, Hall J, Haustermans K, Herskind C, Hoelscher T, Imai T, Iwakawa M, Jones D, Kulich C; EQUAL-ESTRO, Langendijk JH, O’Neils P, Ozsahin M, Parliament M, Polanski A, Rosenstein B, Seminara D, Symonds P, Talbot C, Thierens H, Vega A, West C, Yarnold J. Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1295-6. PMID: 20338472

A Small Interfering RNA Screen of Genes Involved in DNA Repair Identifies Tumor-Specific Radiosensitization by POLQ Knockdown
Higgins GS, Prevo R, Lee YF, Helleday T, Muschel RJ, Taylor S, Yoshimura M, Hickson ID, Bernhard EJ, McKenna WG. Cancer Res. 2010 Mar 16. [Epub ahead of print]PMID: 20233878

Modulating tumor vasculature through signaling inhibition to improve cytotoxic therapy
Maity A, Bernhard EJ. Cancer Res. 2010 Mar 15;70(6):2141-5. Epub 2010 Feb 23.PMID: 20179191

Triage dose assessment for partial-body exposure: dicentric analysis
Prasanna PG, Moroni M, Pellmar TC. Health Phys. 2010 Feb;98(2):244-51.PMID: 20065689

Synopsis of partial-body radiation diagnostic biomarkers and medical management of radiation injury workshop.
Prasanna PG, Blakely WF, Bertho JM, Chute JP, Cohen EP, Goans RE, Grace MB, Lillis-Hearne PK, Lloyd DC, Lutgens LC, Meineke V, Ossetrova NI, Romanyukha A, Saba JD, Weisdorf DJ, Wojcik A, Yukihara EG, Pellmar TC. Radiat Res. 2010 Feb;173(2):245-53. doi: 10.1667/RR1993.1.